α-Enolase could be part of a group of universal cellular sensors that respond to multiple different stimuli. α-Enolase could be considered as a marker of pathological stress in a high number of diseases. Similar to the α-enolase, recombinant α-enolase
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also catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate,. The importance of
α-enolase as plasminogen receptor has been determined in several pathologies such as cancer, skeletal myogenesis, rheumatoid arthritis and Alzheimer's disease, among others. α-Enolaseupregulation has also been described in a countless of other pathologies.