Parkinson's disease defect involves vital death of nerve cells in the brain called neurons. Parkinson's disease leads to damage to all the neurons in the brain. Part of these neurons die for dopamine, a chemical that sends messages to control movement and coordination to part of the brain. The dopamine in the brain makes the decline and inability to control movement normally.() It would affect all the activities of daily life, including talking, hiking ingestion and writing. There are also other issues, such as fatigue, pain, depression, dementia, impulsive and compulsive behavior and problems of continence, which have a significant impact on people's daily lives. The severity of symptoms can fluctuate from day to day and quickly change during the day. Some people with the condition that can face sudden 'freeze'. There is currently no cure. ()